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Cell Bank Origin of MDCK Parental Cells Shapes Adaptation to Serum-Free Suspension Culture and Canine Adenoviral Vector Production

Phenotypic variation in cultured mammalian cell lines is known to be induced by passaging and culture conditions. Yet, the effect these variations have on the production of viral vectors has been overlooked. In this work we evaluated the impact of using Madin–Darby canine kidney (MDCK) parental cell...

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Bibliografiska uppgifter
I publikationen:Int J Mol Sci
Huvudupphovsmän: Rodrigues, Ana Filipa, Fernandes, Paulo, Laske, Tanja, Castro, Rute, Alves, Paula Marques, Genzel, Yvonne, Coroadinha, Ana Sofia
Materialtyp: Artigo
Språk:Inglês
Publicerad: MDPI 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7504089/
https://ncbi.nlm.nih.gov/pubmed/32854295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21176111
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