Arachidonic Acid Metabolites of CYP450 Enzymes and HIF-1α Modulate Endothelium-Dependent Vasorelaxation in Sprague-Dawley Rats under Acute and Intermittent Hyperbaric Oxygenation

Acetylcholine-induced vasorelaxation (AChIR) and responses to reduced pO(2) (hypoxia-induced relaxation (HIR), 0% O(2)) were assessed in vitro in aortic rings of healthy male Sprague-Dawley rats (N = 252) under hyperbaric (HBO(2)) protocols. The studied groups consisted of the CTRL group (untreated)...

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Détails bibliographiques
Publié dans:Int J Mol Sci
Auteurs principaux: Mihaljević, Zrinka, Matić, Anita, Stupin, Ana, Frkanec, Ruža, Tavčar, Branka, Kelava, Vanja, Tartaro Bujak, Ivana, Kolobarić, Nikolina, Kibel, Aleksandar, Drenjančević, Ines
Format: Artigo
Langue:Inglês
Publié: MDPI 2020
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7503979/
https://ncbi.nlm.nih.gov/pubmed/32883025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21176353
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