Genome-wide chromosomal instability by cell-free DNA sequencing predicts survival in patients with metastatic breast cancer

BACKGROUND: Genome-wide chromosomal instability, instead of specific somatic mutations or copy-number alterations in selected genes, is a significant property of cancer and may suggest a new strategy for treatment. Here we utilized cell-free DNA (cfDNA) sequencing to display the whole picture of chr...

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Detalhes bibliográficos
Publicado no:Breast
Main Authors: Mo, Hongnan, Wang, Xiaobing, Ma, Fei, Qian, Ziliang, Sun, Xiaoying, Yi, Zongbi, Guan, Xiuwen, Li, Lixi, Liu, Binliang, Xu, Binghe
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7503795/
https://ncbi.nlm.nih.gov/pubmed/32738630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.breast.2020.07.004
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