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Hepatitis B Virus preS/S Truncation Mutant rtM204I/sW196* Increases Carcinogenesis through Deregulated HIF1A, MGST2, and TGFbi

Inevitable long-term therapy with nucleos(t)ide analogs in patients with chronic hepatitis B virus (HBV) infection has selected reverse-transcriptase (rt) mutants in a substantial proportion of patients. Some of these mutants introduce premature stop codons in the overlapping surface (s) gene, inclu...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Lai, Ming-Wei, Liang, Kung-Hao, Yeh, Chau-Ting
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7503731/
https://ncbi.nlm.nih.gov/pubmed/32887289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21176366
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