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Identification of Potential Chemical Substrates as Fuel for Hypoxic Tumors That May Be Linked to Invadopodium Formation in Hypoxia-Induced MDA-MB-231 Breast-Cancer Cell Line

Hypoxia plays a significant role in solid tumors by the increased expression of hypoxia-inducible factor-1α (HIF-1α), which is known to promote cancer invasion and metastasis. Cancer-cell invasion dynamically begins with the degradation of the extracellular matrix (ECM) via invadopodia formation. Th...

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Vydáno v:Molecules
Hlavní autoři: Hamad, Hamad Ali, Enezei, Hamid Hammad, Alrawas, Anmar, Zakuan, Noraina Muhamad, Abdullah, Nurul Akmaryanti, Cheah, Yoke Kqueen, Hashim, Nur Fariesha Md
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7503683/
https://ncbi.nlm.nih.gov/pubmed/32858793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25173876
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