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Mast Cells Limit Ear Swelling Independently of the Chymase Mouse Mast Cell Protease 4 in an MC903-Induced Atopic Dermatitis-Like Mouse Model

Atopic dermatitis (AD) is a complex, often lifelong allergic disease with severe pruritus affecting around 10% of both humans and dogs. To investigate the role of mast cells (MCs) and MC-specific proteases on the immunopathogenesis of AD, a vitamin D(3)-analog (MC903) was used to induce clinical AD-...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Principais autores: Svanberg, Sofie, Li, Zhiqiang, Öhlund, Pontus, Roy, Ananya, Åbrink, Magnus
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7503626/
https://ncbi.nlm.nih.gov/pubmed/32878208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21176311
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