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The Role of the Kynurenine Signaling Pathway in Different Chronic Pain Conditions and Potential Use of Therapeutic Agents

Tryptophan (TRP) is an essential, aromatic amino acid catabolized by indoleamine 2,3-dioxygenase (IDO) and tryptophan 2,3-dioxygenase (TDO) enzymes into kynurenine. The IDO enzyme is expressed in peripheral tissues and the central nervous system. Another enzyme of interest in the kynurenine signalin...

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Bibliografiska uppgifter
I publikationen:Int J Mol Sci
Huvudupphovsmän: Jovanovic, Filip, Candido, Kenneth D., Knezevic, Nebojsa Nick
Materialtyp: Artigo
Språk:Inglês
Publicerad: MDPI 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7503462/
https://ncbi.nlm.nih.gov/pubmed/32842609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21176045
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