Cell–cell adhesion and 3D matrix confinement determine jamming transitions in breast cancer invasion

Plasticity of cancer invasion and metastasis depends on the ability of cancer cells to switch between collective and single-cell dissemination, controlled by cadherin-mediated cell–cell junctions. In clinical samples, E-cadherin-expressing and -deficient tumours both invade collectively and metastas...

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Detalhes bibliográficos
Publicado no:Nat Cell Biol
Main Authors: Ilina, Olga, Gritsenko, Pavlo G., Syga, Simon, Lippoldt, Jürgen, La Porta, Caterina A. M., Chepizhko, Oleksandr, Grosser, Steffen, Vullings, Manon, Bakker, Gert-Jan, Starruß, Jörn, Bult, Peter, Zapperi, Stefano, Käs, Josef A., Deutsch, Andreas, Friedl, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7502685/
https://ncbi.nlm.nih.gov/pubmed/32839548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41556-020-0552-6
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