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Targeting a bacterial DNABII protein with a chimeric peptide immunogen or humanised monoclonal antibody to prevent or treat recalcitrant biofilm-mediated infections

BACKGROUND: Chronic and recurrent bacterial diseases are recalcitrant to treatment due to the ability of the causative agents to establish biofilms, thus development of means to prevent or resolve these structures are greatly needed. Our approach targets the DNABII family of bacterial DNA-binding pr...

詳細記述

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書誌詳細
出版年:EBioMedicine
主要な著者: Novotny, Laura A., Goodman, Steven D., Bakaletz, Lauren O.
フォーマット: Artigo
言語:Inglês
出版事項: Elsevier 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7502671/
https://ncbi.nlm.nih.gov/pubmed/32651162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2020.102867
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