A targeted reactivation of latent HIV-1 using an activator vector in patient samples from acute infection

BACKGROUND: During combined anti-retroviral treatment, a latent HIV reservoir persists within resting memory CD4 T cells that initiates viral recrudescence upon treatment interruption. Strategies for HIV-1 cure have largely focused on latency reversing agents (LRAs) capable of reactivating and elimi...

詳細記述

保存先:
書誌詳細
出版年:EBioMedicine
主要な著者: Mann, Jamie F.S., Pankrac, Joshua, Klein, Katja, McKay, Paul F., King, Deborah F.L., Gibson, Richard, Wijewardhana, Chanuka N., Pawa, Rahul, Meyerowitz, Jodi, Gao, Yong, Canaday, David H., Avino, Mariano, Poon, Art F.Y., Foster, Caroline, Fidler, Sarah, Shattock, Robin J., Arts, Eric J.
フォーマット: Artigo
言語:Inglês
出版事項: Elsevier 2020
主題:
Research Paper
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7502668/
https://ncbi.nlm.nih.gov/pubmed/32654992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2020.102853
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