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Diffusion rather than intraflagellar transport likely provides most of the tubulin required for axonemal assembly in Chlamydomonas

Tubulin enters the cilium by diffusion and motor-based intraflagellar transport (IFT). However, the respective contribution of each route in providing tubulin for axonemal assembly remains unknown. Using Chlamydomonas, we attenuated IFT-based tubulin transport of GFP–β-tubulin by altering the IFT74N...

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Detalhes bibliográficos
Publicado no:J Cell Sci
Main Authors: Craft Van De Weghe, Julie, Harris, J. Aaron, Kubo, Tomohiro, Witman, George B., Lechtreck, Karl F.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7502601/
https://ncbi.nlm.nih.gov/pubmed/32801124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.249805
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