Limited proliferation capacity of aorta intima resident macrophages requires monocyte recruitment for atherosclerotic plaque progression

Early atherosclerosis depends upon responses by immune cells resident in the intimal aortic wall. Specifically, the healthy intima is thought to be populated by vascular dendritic cells (DC) that, during hypercholesterolemia, initiate atherosclerosis by being the first to accumulate cholesterol. Whe...

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Publicat a:Nat Immunol
Autors principals: Williams, Jesse W., Zaitsev, Konstantin, Kim, Ki-Wook, Ivanov, Stoyan, Saunders, Brian T., Schrank, Patricia R., Kim, Kyeongdae, Elvington, Andrew, Kim, Seung Hyeon, Tucker, Christopher G., Wohltmann, Mary, Fife, Brian T., Epelman, Slava, Artyomov, Maxim N., Lavine, Kory J., Zinselmeyer, Bernd H., Choi, Jae-Hoon, Randolph, Gwendalyn J.
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7502558/
https://ncbi.nlm.nih.gov/pubmed/32895539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41590-020-0768-4
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