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Reducing monocarboxylate transporter MCT1 worsens experimental diabetic peripheral neuropathy

Diabetic peripheral neuropathy (DPN) is one of the most common complications in diabetic patients. Though the exact mechanism for DPN is unknown, it clearly involves metabolic dysfunction and energy failure in multiple cells within the peripheral nervous system. Lactate is an alternate source of met...

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Vydáno v:Exp Neurol
Hlavní autoři: Jha, Mithilesh Kumar, Ament, Xanthe H., Yang, Fang, Liu, Ying, Polydefkis, Michael J., Pellerin, Luc, Morrison, Brett M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7502508/
https://ncbi.nlm.nih.gov/pubmed/32717355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2020.113415
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