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Mesencephalic Astrocyte-Derived Neurotrophic Factor, a Prognostic Factor of Cholangiocarcinoma, Affects Sorafenib Sensitivity of Cholangiocarcinoma Cells by Deteriorating ER Stress

PURPOSE: Intrahepatic cholangiocarcinoma (ICC) is an aggressive malignant tumor characterized by high malignancy and poor prognosis. Although the efficacy of sorafenib against cholangiocarcinoma cell lines has been demonstrated in vivo and in vitro, limited clinical data are available on the efficacy...

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Bibliografische gegevens
Gepubliceerd in:Onco Targets Ther
Hoofdauteurs: He, Jingyi, Li, Guangbing, Liu, Xihan, Ma, Liye, Zhang, Jiayao, Zheng, Shunzhen, Wang, Jianping, Liu, Jun
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Dove 2020
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7502388/
https://ncbi.nlm.nih.gov/pubmed/32982305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S245575
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