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Apoptotic stress induces Bax-dependent, caspase-independent redistribution of LINC complex nesprins
The canonical function of Bcl-2 family proteins is to regulate mitochondrial membrane integrity. In response to apoptotic signals the multi-domain pro-apoptotic proteins Bax and Bak are activated and perforate the mitochondrial outer membrane by a mechanism which is inhibited by their interaction wi...
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| Publicado no: | Cell Death Discov |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7501853/ https://ncbi.nlm.nih.gov/pubmed/33024575 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41420-020-00327-6 |
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