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Arg-Gly-Asp-modified elastin-like polypeptide regulates cell proliferation and cell cycle proteins via the phosphorylation of Erk and Akt in pancreatic β-cell.

OBJECTIVE: Enhancement of β-cell proliferation plays an important role in maintaining β-cell mass and function, and in improving pancreatic β-cell survival before transplantation. Extracellular matrix (ECM) components increase the adhesion and proliferation of β-cells, and the RGD-modified elastin-l...

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Detalhes bibliográficos
Publicado no:Heliyon
Main Authors: Hwang, Yeo Jin, Jung, Gwon-Soo, Jeon, Won Bae, Lee, Kyeong-Min
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7501433/
https://ncbi.nlm.nih.gov/pubmed/32995613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.heliyon.2020.e04918
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