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Structural and mechanistic basis of capsule O-acetylation in Neisseria meningitidis serogroup A
O-Acetylation of the capsular polysaccharide (CPS) of Neisseria meningitidis serogroup A (NmA) is critical for the induction of functional immune responses, making this modification mandatory for CPS-based anti-NmA vaccines. Using comprehensive NMR studies, we demonstrate that O-acetylation stabiliz...
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| Izdano u: | Nat Commun |
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| Glavni autori: | , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group UK
2020
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7501274/ https://ncbi.nlm.nih.gov/pubmed/32948778 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-18464-y |
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