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Induction of protection in mice against a respiratory challenge by a vaccine formulated with exosomes isolated from Chlamydia muridarum infected cells

The goal of this study was to determine if exosomes, isolated from Chlamydia muridarum infected HeLa cells (C. muridarum-exosomes), induce protective immune responses in mice following vaccination using CpG plus Montanide as adjuvants. Exosomes, collected from uninfected HeLa cells and PBS, formulat...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:NPJ Vaccines
Hauptverfasser: Pal, Sukumar, Mirzakhanyan, Yeva, Gershon, Paul, Tifrea, Delia F., de la Maza, Luis M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7501220/
https://ncbi.nlm.nih.gov/pubmed/33014435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41541-020-00235-x
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