CXCR2 signaling promotes secretory cancer-associated fibroblasts in pancreatic ductal adenocarcinoma

Pancreatic ductal adenocarcinoma (PDAC) remains one of the most challenging malignancies. Desmoplasia and tumor-supporting inflammation are hallmarks of PDAC. The tumor microenvironment contributes significantly to tumor progression and spread. Cancer-associated fibroblasts (CAFs) facilitate therapy...

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Veröffentlicht in:FASEB J
Hauptverfasser: Awaji, Mohammad, Saxena, Sugandha, Wu, Lingyun, Prajapati, Dipakkumar R., Purohit, Abhilasha, Varney, Michelle L., Kumar, Sushil, Rachagani, Satyanarayana, Ly, Quan P., Jain, Maneesh, Batra, Surinder K., Singh, Rakesh K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7501205/
https://ncbi.nlm.nih.gov/pubmed/32453916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201902990R
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