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A Potential New Role of ATM Inhibitor in Radiotherapy: Suppressing Ionizing Radiation-Activated EGFR

PURPOSE: Although EGFR inhibitor (EGFRi) is used in cancer therapy to suppress tumor growth and resistance to treatment including radiotherapy, EGFRi resistance frequently developed, which significantly reduced treatment outcomes. Therefore, developing alternative approaches for EGFRi is of great im...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Int J Radiat Biol
Hauptverfasser: Tang, Siyuan, Li, Zhentian, Yang, Lifang, Shen, Liangfang, Wang, Ya
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7500639/
https://ncbi.nlm.nih.gov/pubmed/31859574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/09553002.2020.1707325
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