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Serum miRNAs Are Pharmacodynamic Biomarkers Associated With Therapeutic Response in Pediatric Inflammatory Bowel Disease

BACKGROUND: We sought to identify microRNAs (miRNAs) associated with response to anti-TNF-α or glucocorticoids in children with inflammatory bowel disease (IBD) to generate candidate pharmacodynamic and monitoring biomarkers. METHODS: Clinical response was assessed by Pediatric Crohn’s Disease Activ...

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Detalhes bibliográficos
Publicado no:Inflamm Bowel Dis
Main Authors: Batra, Suruchi K, Heier, Christopher R, Diaz-Calderon, Lina, Tully, Christopher B, Fiorillo, Alyson A, van den Anker, John, Conklin, Laurie S
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7500519/
https://ncbi.nlm.nih.gov/pubmed/32793975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ibd/izaa209
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