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Xenometabolite signatures in the UC Davis type 2 diabetes mellitus rat model revealed using a metabolomics platform enriched with microbe-derived metabolites

The gut microbiome has the potential to create or modify xenometabolites (i.e., nonhost-derived metabolites) through de novo synthesis or modification of exogenous and endogenous compounds. While there are isolated examples of xenometabolites influencing host health and disease, wide-scale character...

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Опубликовано в: :Am J Physiol Gastrointest Liver Physiol
Главные авторы: Mercer, Kelly E., Yeruva, Laxmi, Pack, Lindsay, Graham, James L., Stanhope, Kimber L., Chintapalli, Sree V., Wankhade, Umesh D., Shankar, Kartik, Havel, Peter J., Adams, Sean H., Piccolo, Brian D.
Формат: Artigo
Язык:Inglês
Опубликовано: American Physiological Society 2020
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7500265/
https://ncbi.nlm.nih.gov/pubmed/32508155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00105.2020
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