Enhanced lipid biosynthesis in human tumor-induced macrophages contributes to their protumoral characteristics

BACKGROUND: Tumor-associated macrophages (TAMs) are key components of the tumor microenvironment (TME) in non-medullary thyroid carcinoma (TC) and neuroblastoma (NB), being associated with a poor prognosis for patients. However, little is known about how tumors steer the specific metabolic phenotype...

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Detalhes bibliográficos
Publicado no:J Immunother Cancer
Main Authors: Rabold, Katrin, Aschenbrenner, Anna, Thiele, Christoph, Boahen, Collins K, Schiltmans, Alexander, Smit, Johannes W A, Schultze, Joachim L, Netea, Mihai G, Adema, Gosse J, Netea-Maier, Romana T
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2020
Assuntos:
Basic Tumor Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7500191/
https://ncbi.nlm.nih.gov/pubmed/32943450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2020-000638
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