Crocetin Overproduction in Engineered Saccharomyces cerevisiae via Tuning Key Enzymes Coupled With Precursor Engineering

Crocetin, an important natural carotenoid dicarboxylic acid with high pharmaceutical values, has been successfully generated from glucose by engineered Saccharomyces cerevisiae in our previous study. Here, a systematic optimization was executed for crocetin overproduction in yeast. The effects of pr...

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Veröffentlicht in:Front Bioeng Biotechnol
Hauptverfasser: Song, Tianqing, Wu, Nan, Wang, Chen, Wang, Ying, Chai, Fenghua, Ding, Mingzhu, Li, Xia, Yao, Mingdong, Xiao, Wenhai, Yuan, Yingjin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Bioengineering and Biotechnology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7500066/
https://ncbi.nlm.nih.gov/pubmed/33015027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2020.578005
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