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Role of HVR1 sequence similarity in the cross-genotypic neutralization of HCV

Despite available treatments, a prophylactic HCV vaccine is needed to achieve elimination targets. HCV vaccine development has faltered largely because the extreme diversity of the virus limits the protective breadth of vaccine elicited antibodies. It is believed that the principle neutralizing epit...

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Detalles Bibliográficos
Publicado en:Virol J
Main Authors: Mosa, Alexander I., AbouHaidar, Mounir G., Urbanowicz, Richard A., Tavis, John E., Ball, Jonathan K., Feld, Jordan J.
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7499410/
https://ncbi.nlm.nih.gov/pubmed/32948191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12985-020-01408-9
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