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APOE2 promotes the development and progression of subretinal neovascularization in age-related macular degeneration via MAPKs signaling pathway

BACKGROUND: Neovascular age-related macular degeneration (nvAMD) is one of the main pathological features of wet AMD. Apolipoprotein E2 is involved in the formation of nvAMD but the molecular mechanism has not been reported. METHODS: The APOE alleles in AMD patients were detected by genotyping. Mous...

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Publicat a:Saudi J Biol Sci
Autors principals: Sun, Yiwen, Song, Ruixia, Ai, Yanliang, Zhu, Jianjun, He, Jun, Dang, Minyan, Li, Hui
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7499293/
https://ncbi.nlm.nih.gov/pubmed/32994736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sjbs.2020.06.037
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