Potential pharmacodynamic and pharmacokinetic interactions of Nigella Sativa and Trigonella Foenum-graecum with losartan in L-NAME induced hypertensive rats

The objective of this investigation was to study whether Nigella Sativa and Trigonella Foenum-graecum, could modulate the losartan pharmacodynamic (PD) and pharmacokinetic (PK) in experimental L-NAME induced hypertensive rats. For in vivo study, the systolic blood pressure (SBP) of rats was measured...

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Udgivet i:Saudi J Biol Sci
Main Authors: Ahad, Abdul, Raish, Mohammad, Bin Jardan, Yousef A., Alam, Mohd Aftab, Al-Mohizea, Abdullah M., Al-Jenoobi, Fahad I.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2020
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7499079/
https://ncbi.nlm.nih.gov/pubmed/32994710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sjbs.2020.05.009
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