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Ouabain-Induced Cell Death and Survival. Role of α1-Na,K-ATPase-Mediated Signaling and [Na(+)](i)/[K(+)](i)-Dependent Gene Expression
Ouabain is of cardiotonic steroids (CTS) family that is plant-derived compounds and is known for many years as therapeutic and cytotoxic agents. They are specific inhibitors of Na,K-ATPase, the enzyme, which pumps Na(+) and K(+) across plasma membrane of animal cells. Treatment of cells by CTS affec...
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| Publicado no: | Front Physiol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7498651/ https://ncbi.nlm.nih.gov/pubmed/33013454 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2020.01060 |
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