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Wnt/β-catenin signaling pathway induces autophagy-mediated temozolomide-resistance in human glioblastoma

Temozolomide (TMZ) is widely used for treating glioblastoma multiforme (GBM), however, the treatment of such brain tumors remains a challenge due to the development of resistance. Increasing studies have found that TMZ treatment could induce autophagy that may link to therapeutic resistance in GBM,...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Yun, Eun-Jin, Kim, Sangwoo, Hsieh, Jer-Tsong, Baek, Seung Tae
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7498596/
https://ncbi.nlm.nih.gov/pubmed/32943609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-02988-8
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