Oxidative stress-mediated mitochondrial dysfunction facilitates mesenchymal stem cell senescence in ankylosing spondylitis

Ankylosing spondylitis (AS) is a chronic inflammatory disease possessing a morbid serum microenvironment with enhanced oxidative stress. Long-term exposure to an oxidative environment usually results in cellular senescence alone with cellular dysfunction. Mesenchymal stem cells (MSCs) are a kind of...

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Pubblicato in:Cell Death Dis
Autori principali: Ye, Guiwen, Xie, Zhongyu, Zeng, Huiqiong, Wang, Peng, Li, Jinteng, Zheng, Guan, Wang, Shan, Cao, Qian, Li, Ming, Liu, Wenjie, Cen, Shuizhong, Li, Zhaofeng, Wu, Yanfeng, Ye, Zhizhong, Shen, Huiyong
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7498590/
https://ncbi.nlm.nih.gov/pubmed/32943613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-02993-x
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