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Extracellular bacterial lymphatic metastasis drives Streptococcus pyogenes systemic infection

Unassisted metastasis through the lymphatic system is a mechanism of dissemination thus far ascribed only to cancer cells. Here, we report that Streptococcus pyogenes also hijack lymphatic vessels to escape a local infection site, transiting through sequential lymph nodes and efferent lymphatic vess...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Siggins, Matthew K., Lynskey, Nicola N., Lamb, Lucy E., Johnson, Louise A., Huse, Kristin K., Pearson, Max, Banerji, Suneale, Turner, Claire E., Woollard, Kevin, Jackson, David G., Sriskandan, Shiranee
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7498588/
https://ncbi.nlm.nih.gov/pubmed/32943639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-18454-0
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