HDAC8: A Promising Therapeutic Target for Acute Myeloid Leukemia

Histone deacetylase 8 (HDAC8), a class I HDAC that modifies non-histone proteins such as p53, is highly expressed in different hematological neoplasms including a subtype of acute myeloid leukemia (AML) bearing inversion of chromosome 16 [inv(16)]. To investigate HDAC8 contribution to hematopoietic...

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Bibliografske podrobnosti
izdano v:Front Cell Dev Biol
Main Authors: Spreafico, Marco, Gruszka, Alicja M., Valli, Debora, Mazzola, Mara, Deflorian, Gianluca, Quintè, Arianna, Totaro, Maria Grazia, Battaglia, Cristina, Alcalay, Myriam, Marozzi, Anna, Pistocchi, Anna
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2020
Teme:
Cell and Developmental Biology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7498549/
https://ncbi.nlm.nih.gov/pubmed/33015043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.00844
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