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The peroxisome counteracts oxidative stresses by suppressing catalase import via Pex14 phosphorylation

Most of peroxisomal matrix proteins including a hydrogen peroxide (H(2)O(2))-decomposing enzyme, catalase, are imported in a peroxisome-targeting signal type-1 (PTS1)-dependent manner. However, little is known about regulation of the membrane-bound protein import machinery. Here, we report that Pex1...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:eLife
Hauptverfasser: Okumoto, Kanji, El Shermely, Mahmoud, Natsui, Masanao, Kosako, Hidetaka, Natsuyama, Ryuichi, Marutani, Toshihiro, Fujiki, Yukio
Format: Artigo
Sprache:Inglês
Veröffentlicht: eLife Sciences Publications, Ltd 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7498260/
https://ncbi.nlm.nih.gov/pubmed/32831175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.55896
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