PINK1 alleviates thermal hypersensitivity in a paclitaxel-induced Drosophila model of peripheral neuropathy

Paclitaxel is a representative anticancer drug that induces chemotherapy-induced peripheral neuropathy (CIPN), a common side effect that limits many anticancer chemotherapies. Although PINK1, a key mediator of mitochondrial quality control, has been shown to protect neuronal cells from various toxic...

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Publicado en:PLoS One
Autores principales: Kim, Young Yeon, Yoon, Jeong-Hyun, Um, Jee-Hyun, Jeong, Dae Jin, Shin, Dong Jin, Hong, Young Bin, Kim, Jong Kuk, Kim, Dong Hyun, Kim, Changsoo, Chung, Chang Geon, Lee, Sung Bae, Koh, Hyongjong, Yun, Jeanho
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7498067/
https://ncbi.nlm.nih.gov/pubmed/32941465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0239126
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