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Models with interactions overestimated heterogeneity of treatment effects and were prone to treatment mistargeting

OBJECTIVES: We aimed to compare the performance of different regression modelling approaches for the prediction of heterogeneous treatment effects. STUDY DESIGN AND SETTING: We simulated trial samples (n=3,600; 80% power for a treatment odds ratio of 0.8) from a superpopulation (N=1.000.000) with 12...

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Bibliografske podrobnosti
izdano v:J Clin Epidemiol
Main Authors: van Klaveren, David, Balan, Theodor A., Steyerberg, Ewout W., Kent, David M.
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7497896/
https://ncbi.nlm.nih.gov/pubmed/31195109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jclinepi.2019.05.029
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