Microglial Remodeling of the Extracellular Matrix Promotes Synapse Plasticity

Synapse remodeling is essential to encode experiences into neuronal circuits. Here, we define a molecular interaction between neurons and microglia that drives experience-dependent synapse remodeling in the hippocampus. We find that the cytokine interleukin-33 (IL-33) is expressed by adult hippocamp...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell
Prif Awduron: Nguyen, Phi T., Dorman, Leah C., Pan, Simon, Vainchtein, Ilia D., Han, Rafael T., Nakao-Inoue, Hiromi, Taloma, Sunrae E., Barron, Jerika J., Molofsky, Ari B., Kheirbek, Mazen A., Molofsky, Anna V.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2020
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7497728/
https://ncbi.nlm.nih.gov/pubmed/32615087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2020.05.050
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