Identification of candidate mediators of chemoresponse in breast cancer through therapy-driven selection of somatic variants

PURPOSE: More than a third of primary breast cancer patients are treated with cytotoxic chemotherapy, typically without guidance from predictive markers. Increased use of neoadjuvant chemotherapy provides opportunities for identification of molecules associated with treatment response, by comparing...

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Vydáno v:Breast Cancer Res Treat
Hlavní autoři: Al Amri, Waleed S., Baxter, Diana E., Hanby, Andrew M., Stead, Lucy F., Verghese, Eldo T., Thorne, James L., Hughes, Thomas A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer US 2020
Témata:
Preclinical Study
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7497675/
https://ncbi.nlm.nih.gov/pubmed/32734521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-020-05836-7
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