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Synthesis of Trifluoromethylated Purine Ribonucleotides and Their Evaluation as (19)F NMR Probes
[Image: see text] Protected guanosine and adenosine ribonucleosides and guanine nucleotides are readily functionalized with CF(3) substituents within the nucleobase. Protected guanosine is trifluoromethylated at the C8 position under radical-generating conditions in up to 95% yield and guanosine 5′-...
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| Publicado no: | J Org Chem |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical Society
2020
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7497640/ https://ncbi.nlm.nih.gov/pubmed/31994393 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.9b03198 |
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