Ruthenium-Mediated (18)F-Fluorination and Preclinical Evaluation of a New CB(1) Receptor Imaging Agent [(18)F]FPATPP

[Image: see text] Cannabinoid receptor 1 (CB1R) controls various physiological and pathological conditions, including memory, motivation, and inflammation, and is thus an interesting target for positron emission tomography (PET). Herein, we report a ruthenium-mediated radiolabeling synthesis and pre...

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Bibliografiske detaljer
Udgivet i:ACS Chem Neurosci
Main Authors: Lahdenpohja, Salla, Rajala, Noora A., Helin, Jatta S., Haaparanta-Solin, Merja, Solin, Olof, López-Picón, Francisco R., Kirjavainen, Anna K.
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2020
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7497626/
https://ncbi.nlm.nih.gov/pubmed/32479723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.0c00313
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