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Mechanosensitive regulation of stanniocalcin‐1 by zyxin and actin‐myosin in human mesenchymal stromal cells

Stanniocalcin‐1 (STC1) secreted by mesenchymal stromal cells (MSCs) has anti‐inflammatory functions, reduces apoptosis, and aids in angiogenesis, both in vitro and in vivo. However, little is known about the molecular mechanisms of its regulation. Here, we show that STC1 secretion is increased only...

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Vydáno v:Stem Cells
Hlavní autoři: Zonderland, Jip, Gomes, David B., Pallada, Yves, Moldero, Ivan L., Camarero‐Espinosa, Sandra, Moroni, Lorenzo
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley & Sons, Inc. 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7497098/
https://ncbi.nlm.nih.gov/pubmed/32379914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.3198
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