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Mechanosensitive regulation of stanniocalcin‐1 by zyxin and actin‐myosin in human mesenchymal stromal cells

Stanniocalcin‐1 (STC1) secreted by mesenchymal stromal cells (MSCs) has anti‐inflammatory functions, reduces apoptosis, and aids in angiogenesis, both in vitro and in vivo. However, little is known about the molecular mechanisms of its regulation. Here, we show that STC1 secretion is increased only...

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Detalles Bibliográficos
Publicado en:Stem Cells
Main Authors: Zonderland, Jip, Gomes, David B., Pallada, Yves, Moldero, Ivan L., Camarero‐Espinosa, Sandra, Moroni, Lorenzo
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley & Sons, Inc. 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7497098/
https://ncbi.nlm.nih.gov/pubmed/32379914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.3198
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