Utility of systemic voriconazole in equine keratomycosis based on pharmacokinetic‐pharmacodynamic analysis of tear fluid following oral administration

OBJECTIVE: To clarify the detailed pharmacokinetics (PK) of orally administered voriconazole in tear fluid (TF) of horses for evaluating the efficacy of voriconazole secreted into TF against equine keratomycosis. ANIMALS STUDIED: Five healthy Thoroughbred horses. PROCEDURES: Voriconazole was adminis...

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Bibliografiske detaljer
Udgivet i:Vet Ophthalmol
Main Authors: Tamura, Norihisa, Okano, Atsushi, Kuroda, Taisuke, Niwa, Hidekazu, Kusano, Kanichi, Matsuda, Yoshikazu, Fukuda, Kentaro, Mita, Hiroshi, Nagata, Shunichi
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2020
Fag:
Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7496923/
https://ncbi.nlm.nih.gov/pubmed/32383526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/vop.12764
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