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Deletion of astrocytic BMAL1 results in metabolic imbalance and shorter lifespan in mice
Disruption of the circadian cycle is strongly associated with metabolic imbalance and reduced longevity in humans. Also, rodent models of circadian arrhythmia, such as the constitutive knockout of the clock gene Bmal1, leads to metabolic disturbances and early death. Although astrocyte clock regulat...
Guardat en:
| Publicat a: | Glia |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
John Wiley & Sons, Inc.
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7496695/ https://ncbi.nlm.nih.gov/pubmed/31833591 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.23764 |
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