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Clinical and pathogenic aspects of the severe cutaneous adverse reaction epidermal necrolysis (EN)

The severe cutaneous adverse reaction epidermal necrolysis (EN) which includes toxic epidermal necrolysis and the milder Stevens‐Johnson syndrome is characterized by epidermal loss due to massive keratinocyte apoptosis and/or necroptosis. EN is often caused by a drug mediating a specific TCR‐HLA int...

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Detalhes bibliográficos
Publicado no:J Eur Acad Dermatol Venereol
Main Authors: Kuijper, E.C., French, L.E., Tensen, C.P., Vermeer, M.H., Bouwes Bavinck, J.N.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7496676/
https://ncbi.nlm.nih.gov/pubmed/32415695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jdv.16339
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