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Biological mechanisms underlying inter‐individual variation in factor VIII clearance in haemophilia

Previous studies have highlighted marked inter‐individual variations in factor VIII (FVIII) clearance between patients with haemophilia (PWH). The half‐life of infused FVIII has been reported to vary from as little as 5.3 hours in some adult PWH, up to as long as 28.8 hours in other individuals. The...

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Detalhes bibliográficos
Publicado no:Haemophilia
Main Authors: Turecek, Peter L., Johnsen, Jill M., Pipe, Steven W., O'Donnell, James S.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7496649/
https://ncbi.nlm.nih.gov/pubmed/32596930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/hae.14078
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