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A 24‐base pair deletion in the ABO gene causes a hereditary splice site defect: a novel mechanism underlying ABO blood group O

BACKGROUND: Blood group A and B antigens are synthesized by glycosyltransferases regulated by a complex molecular genetic background. A multibase deletion in the ABO gene was identified in two related blood donors. To define its hereditary character and to evaluate genotype–phenotype associations, a...

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Bibliografiske detaljer
Udgivet i:Transfusion
Main Authors: Matzhold, Eva Maria, Drexler, Camilla, Wagner, Andrea, Bernecker, Claudia, Pessentheiner, Ariane, Bogner‐Strauß, Juliane Gertrude, Helmberg, Wolfgang, Wagner, Thomas
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley & Sons, Inc. 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7496400/
https://ncbi.nlm.nih.gov/pubmed/32500601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/trf.15907
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