FTY720 Protects Against Ischemia–Reperfusion Injury by Preventing the Redistribution of Tight Junction Proteins and Decreases Inflammation in the Subacute Phase in an Experimental Stroke Model

Injury due to brain ischemia followed by reperfusion (I/R) may be an important therapeutic target in the era of thrombectomy. FTY720, a widely known sphingosine-1-phosphate receptor agonist, exerts various neuroprotective effects. The aim of this study was to examine the protective effect of FTY720...

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Опубликовано в: :Transl Stroke Res
Главные авторы: Wang, Zifeng, Higashikawa, Kei, Yasui, Hironobu, Kuge, Yuji, Ohno, Yusuke, Kihara, Akio, Midori, Yenari A., Houkin, Kiyohiro, Kawabori, Masahito
Формат: Artigo
Язык:Inglês
Опубликовано: Springer US 2020
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Original Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7496052/
https://ncbi.nlm.nih.gov/pubmed/32103462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12975-020-00789-x
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