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Bacterial Expression, Purification, and Initial Characterization of a Full-length Cas13b Protein from Porphyromonas gingivalis

The CRISPR-Cas13b system is a recently identified Class 2, RNA-targeting CRISPR-Cas system. The system has been repurposed to achieve robust mRNA knockdown and precise RNA-editing in mammalian cells. While the CRISPR-Cas13b system has become a powerful tool for nucleic acids manipulation, the mechan...

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Foilsithe in:Protein Expr Purif
Main Authors: Zhu, Jiang, Zhou, Xia, Huang, Xiaolan, Du, Zhihua
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2020
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Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7495503/
https://ncbi.nlm.nih.gov/pubmed/32006655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pep.2020.105588
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