Antiviral Properties of the LSD1 Inhibitor SP-2509

Lysine-specific demethylase 1 (LSD1) targets cellular proteins, including histone H3, p53, E2F, and Dnmt1, and is involved in the regulation of gene expression, DNA replication, the cell cycle, and the DNA damage response. LSD1 catalyzes demethylation of histone H3K9 associated with herpes simplex v...

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Vydáno v:J Virol
Hlavní autoři: Harancher, Mitchell R., Packard, Jessica E., Cowan, Shane P., DeLuca, Neal A., Dembowski, Jill A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2020
Témata:
Genome Replication and Regulation of Viral Gene Expression
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7495396/
https://ncbi.nlm.nih.gov/pubmed/32699090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00974-20
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