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Hemoglobin stimulates vigorous growth of Streptococcus pneumoniae and shapes the pathogen's global transcriptome

Streptococcus pneumoniae (Spn) must acquire iron from the host to establish infection. We examined the impact of hemoglobin, the largest iron reservoir in the body, on pneumococcal physiology. Supplementation with hemoglobin allowed Spn to resume growth in an iron-deplete medium. Pneumococcal growth...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Akhter, Fahmina, Womack, Edroyal, Vidal, Jorge E., Le Breton, Yoann, McIver, Kevin S., Pawar, Shrikant, Eichenbaum, Zehava
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7494912/
https://ncbi.nlm.nih.gov/pubmed/32938947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-71910-1
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