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Monoglyceride lipase mediates tumor-suppressive effects by promoting degradation of X-linked inhibitor of apoptosis protein

We have previously reported that Monoglyceride Lipase (MGL) expression is absent or reduced in various human malignancies and MGL-deficient mice develop tumors in multiple organs. Evidence also suggests MGL to be a tumor suppressor, however, the mechanisms underlying its tumor-suppressive actions re...

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Publié dans:Cell Death Differ
Auteurs principaux: Liu, Renyan, Wang, Xin, Curtiss, Christopher, Sheikh, M. Saeed, Huang, Ying
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2020
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7494902/
https://ncbi.nlm.nih.gov/pubmed/32376875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-020-0549-5
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